CELLS
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INCREASED IN
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DECREASED IN
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Neutrophils
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Infection (bacterial or early viral), acute stress, acute and chronic inflammation, tumors, drugs (eg, G-CSF), diabetic ketoacidosis, leukemia (rare). |
Aplastic anemia, drug-induced neutropenia, chemotherapy, folate or B12 deficiency, myelodysplasia, marrow infiltration, cyclic neutropenia, autoimmune or isoimmune neutropenia, Felty syndrome, hypersplenism, sepsis, viral marrow suppression, bone marrow failure syndromes. |
Lymphocytes
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Viral infection (especially infectious mononucleosis, pertussis), thyrotoxicosis, adrenal insufficiency, lymphoid leukemia/lymphoma, chronic infection, drug and allergic reactions, autoimmune diseases |
Immune deficiency syndromes (eg, HIV), idiopathic drugs. |
Monocytes
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Inflammation, infection, malignancy, tuberculosis, myeloproliferative disorders (eg, CMML) |
Depleted in overwhelming bacterial infection, hairy cell leukemia. |
Eosinophils
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Allergic states, asthma, drug sensitivity reactions, skin disorders, parasitic and certain fungal infections, Churg- Strauss syndrome, polyarteritis nodosa, response to malignancy (eg, Hodgkin disease, T-cell lymphoma, adenocarcinoma), eosinophilic pneumonia, hyper-eosinophilic syndrome, leukemia (eg, chronic eosinophilic leukemia), myeloid or lymphoid neoplasm with abnormalities of PDGF receptor (alpha or beta) or FGF receptor, mastocytosis |
Depleted in overwhelming bacterial infection, hairy cell leukemia |
Basophils
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Hypersensitivity reactions, drugs, myeloproliferative disorders (eg, CML), basophilic or mast cell variant of acute or chronic leukemia, inflammatory reaction, certain infections, hypothyroidism |
Not applicable. |